Proceeding | OPEN ACCESS

Utilization of antimicrobial agents in Federal Neuro-psychiatric Hospital, Uselu, Benin City, Edo State, Nigeria

Upe F Babaiwa , Damilola S Oni, John O Akerele

Department of Pharmaceutical Microbiology, Faculty of Pharmacy, University of Benin, PMB 1154, Benin City, 300001, Nigeria.;

For correspondence:-  Upe Babaiwa   Email:  upe.babaiwa@uniben.edu   Tel:  +2348035467818

Published: 28 December 2018

Citation: Babaiwa UF, Oni DS, Akerele JO. Utilization of antimicrobial agents in Federal Neuro-psychiatric Hospital, Uselu, Benin City, Edo State, Nigeria. J Sci Pract Pharm 2018; 5(1):216-217 doi: 10.47227/jsppharm.v5i1.12

© 2018 The author(s).
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). This license requires that reusers give credit to the creator. It allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, for noncommercial purposes only. .

Abstract

Purpose: This research was aimed to evaluate antimicrobial utilization pattern at a regional Neuro-psychiatric Hospital in Edo State, Nigeria.

Methods: Data were obtained retrospectively from a review of 210 in-patient records between April to June 2017, using standard data collection format. Information collected included; patient demographics, diagnosis, antimicrobial treatment regimen.

Results: A total of 210 patients with a mean age of 20.87 years (± 1.3) were evaluated. Antimicrobials were most frequently prescribed for patients within ages of 21- 60 years (72.86%). Beta lactams and nitro-imidazoles were the most prescribed class of antimicrobials in this study. This may be due to their broad spectrum of activity, clinical efficacy, high safety profile as well as availability and affordability. In line with the Nigerian treatment guideline, nitro-imidazoles are a component of multidrug regimen (in combination with omeprazole, clarithromycin and amoxicillin) for therapy of Helicobacter pylori infections.

Conclusion: This study showed that relevant laboratory investigation was carried out and used as a guide for antibiotic prescription in only 3.33%, indicative of irrational use of antimicrobials. Promoting the rational use of antimicrobials will result in improved quality of life for the patient and the community. There is need to embrace best global practices through mandatory continuing professional development of practitioners. To ensure that they have the necessary knowledge and skills to prescribe rationally, especially in times when combination therapy is of essence.

 

 

 

Keywords: Neuro-psychiatric setting, antimicrobials, lactams, nitro-imidazoles, clarithromycins

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